Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30345075 | 0.86 | ALDH1A1 (0.44) | ALDH1A1NPSR1CDC25ACYP1A2CYP3A4 | |
| SCHEMBL30345051 | 0.86 | CDC25A (0.58) | ALDH1A1NPSR1CDC25ACYP1A2CYP3A4 | |
| SCHEMBL30345114 | 0.82 | CDC25A (0.45) | ALDH1A1NPSR1CDC25ACYP1A2CYP3A4 | |
| SCHEMBL30345008 | 0.82 | EP300 (0.48) | ALDH1A1CDC25ACES2MEN1KMT2A | |
| SCHEMBL30345054 | 0.81 | ALDH1A1 (0.46) | ALDH1A1NPSR1CDC25ACES2LMNA | |
| SCHEMBL30345028 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CDC25ACYP2D6CYP2C9CES2 | |
| SCHEMBL18974998 | 0.77 | ALDH1A1 (0.47) | ALDH1A1NPSR1CDC25ALMNAADORA3 | |
| SCHEMBL23803182 | 0.75 | CES2 (0.41) | ALDH1A1NPSR1CDC25ACES2LMNA | |
| SCHEMBL20495415 | 0.75 | CES2 (0.41) | ALDH1A1NPSR1CDC25ACES2LMNA | |
| SCHEMBL29541496 | 0.73 | BCHE (0.45) | ALDH1A1CDC25ACES2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925609-A | Preparation method of 3-alkenyloxindole derivative | 洛阳师范学院 | 2023-04-07 | — | — | CN | disclosed |