Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 7/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19511024 | 0.80 | HIF1A (0.50) | HIF1ASMN1; SMN2PPARGPPARA | |
| SCHEMBL29505453 | 0.80 | HIF1A (0.50) | HIF1ASMN1; SMN2PPARGPPARA | |
| SCHEMBL4816734 | 0.77 | SMN1; SMN2 (0.51) | HIF1ASMN1; SMN2LPLLIPGCA1 | |
| SCHEMBL6312527 | 0.77 | LIPG (0.42) | ARHIF1ASMN1; SMN2LPLLIPG | |
| SCHEMBL19510955 | 0.77 | PDE3B (0.47) | HIF1APPARG | |
| SCHEMBL1679479 | 0.76 | LPL (0.48) | HIF1ASMN1; SMN2LPLLIPGCA1 | |
| SCHEMBL22816813 | 0.75 | LPL (0.47) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL5780789 | 0.74 | LPL (0.49) | HIF1ASMN1; SMN2LPLLIPGCA1 | |
| SCHEMBL28980457 | 0.74 | HIF1A (0.54) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL29644319 | 0.72 | LPL (0.62) | HIF1ALPLLIPGCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239143-B1 | BIARYL DERIVATIVE AS GPR120 AGONIST | LG CHEMICAL LTD (KR) | 2023-03-22 | — | — | EP | disclosed |