Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435635 | 1.00 | NAAA (0.52) | NAAATSHRTHRBMEN1KMT2A | |
| SCHEMBL271380 | 1.00 | — | — | |
| SCHEMBL303005 | 1.00 | NAAA (0.52) | NAAATSHRTHRBMEN1KMT2A | |
| SCHEMBL4604995 | 1.00 | NAAA (0.52) | NAAATSHRTHRBMEN1KMT2A | |
| SCHEMBL3801573 | 1.00 | NAAA (0.52) | NAAATSHRTHRBMEN1KMT2A | |
| SCHEMBL2536851 | 1.00 | NAAA (0.52) | NAAATSHRTHRBMEN1KMT2A | |
| SCHEMBL56917 | 0.97 | — | — | |
| SCHEMBL9848564 | 0.94 | NAAA (0.52) | NAAATSHRTHRBMEN1KMT2A | |
| SCHEMBL277225 | 0.90 | TSHR (0.61) | NAAATSHRTHRBMEN1KMT2A | |
| SCHEMBL9206028 | 0.90 | TSHR (0.61) | NAAATSHRTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255070-B2 | Method of deuteration using mixed catalyst | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2016-02-09 | — | — | US | disclosed |
| US-8093422-B2 | Method for deuteration of an aromatic ring | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-7517990-B2 | Method for deuteration of a heterocyclic ring | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20080234488-A1 | Method of Deuteration Using Mixed Catalyst | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2008-09-25 | — | — | US | disclosed |
| US-20070255076-A1 | Method for Deuteration of an Aromatic Ring | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| EP-1707548-A1 | METHOD OF DEUTERATION USING MIXED CATALYST | Wako Pure Chemical Industries, Ltd. (JP) | 2006-10-04 | — | — | EP | disclosed |
| US-20060025596-A1 | Method for deuteration or tritiation of heterocyclic ring | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2006-02-02 | — | — | US | disclosed |
| EP-1561741-A1 | METHOD FOR DEUTERATION OR TRITIATION OF HETEROCYCLIC RING | Wako Pure Chemical Industries, Ltd. (JP) | 2005-08-10 | — | — | EP | disclosed |
| EP-1535889-A1 | METHOD OF DEUTERATING AROMATIC RING | Wako Pure Chemical Industries, Ltd. (JP) | 2005-06-01 | — | — | EP | disclosed |
| EP-0929609-B1 | SUBSTITUTED PHTHALOCYANINES AND THEIR USE | CIBA SC HOLDING AG (CH) | 2002-06-19 | — | — | EP | disclosed |
| US-6087492-A | METALLIZED PHTHALOCYANINE DYES | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-07-11 | — | — | US | disclosed |
| EP-0929609-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR USE | Ciba SC Holding AG (CH) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998014520-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR USE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025596-A1 | Method for deuteration or tritiation of heterocyclic ring | HRH2, HRH4, HDHD5 | NAAA 566/4885TSHR 1299/4885THRB 3448/4885 |
| US-20080234488-A1 | Method of Deuteration Using Mixed Catalyst | HDHD5, DHX35, HRH3 | NAAA 490/4885TSHR 2222/4885THRB 4403/4885 |
| US-20070255076-A1 | Method for Deuteration of an Aromatic Ring | HRH3, HRH4, AHR | NAAA 338/4885TSHR 2185/4885THRB 4024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.