⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3567117 | 0.83 | — | — | |
| SCHEMBL7312600 | 0.81 | CES2 (0.40) | — | |
| SCHEMBL840682 | 0.80 | — | — | |
| SCHEMBL9736433 | 0.80 | — | — | |
| SCHEMBL7308569 | 0.79 | MEN1 (0.43) | — | |
| SCHEMBL4520517 | 0.78 | — | — | |
| SCHEMBL818329 | 0.78 | CES2 (0.41) | — | |
| SCHEMBL817979 | 0.78 | CES2 (0.41) | — | |
| SCHEMBL818629 | 0.78 | CES2 (0.41) | — | |
| SCHEMBL1086960 | 0.78 | CES2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852420-B1 | Indole compounds for treating respiratory disorders | ONO PHARMACEUTICAL CO (JP) | 2012-10-17 | — | — | EP | claimed |
| EP-1852420-B1 | Indole compounds for treating respiratory disorders | ONO PHARMACEUTICAL CO (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-20100216791-A1 | PYRIDINYLQUINAZOLINAMINE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS | ASTRAZENECA (SE) | 2010-08-26 | — | — | US | disclosed |
| US-7728023-B2 | Indole compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20080188532-A1 | Indole Compound and Use Thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-08-07 | — | — | US | disclosed |
| WO-2008020203-A1 | PYRIDINYLQUINAZ0LINAMINE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS | ASTRAZENECA AB (SE) | 2008-02-21 | — | — | WO | disclosed |
| US-7320973-B2 | Dihydrodiaryloxazepine derivative and pharmaceutical composition containing the same | AJINOMOTO CO., INC. (JP) | 2008-01-22 | — | — | US | disclosed |
| EP-1852420-A1 | INDOLE COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-11-07 | — | — | EP | disclosed |
| WO-2005028486-A1 | METHODS OF REFINING SILANE COMPOUNDS | HONEYWELL INTERNATIONAL INC. (US) | 2005-03-31 | — | — | WO | disclosed |
| US-20050059835-A1 | Methods of refining silane compounds | HONEYWELL INTERNATIONAL INC. (US) | 2005-03-17 | — | — | US | disclosed |
| US-5523325-A | INSECTICIDES | DOW AGROSCIENCES LLC, A DELAWARE LIMITED LIABILITY COMPANY | 1996-06-04 | — | — | US | disclosed |
| US-5459147-A | Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma | DR. KARL THOMAE GMBH (DE) | 1995-10-17 | — | — | US | disclosed |
| EP-0643040-A1 | Amidrazones and their use as pesticides | ROHM AND HAAS COMPANY (US) | 1995-03-15 | — | — | EP | disclosed |
| US-5357025-A | Reaction product of hydrolyzable silane component and fluorocarbon alcohol cured with polysiloxane | DOW CORNING CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0587295-A1 | Sealant with siloxaphobic surface, composition and method to prepare same | DOW CORNING CORPORATION (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0586184-A2 | Polydimethylsiloxanes for modulus reduction and method for their preparation | DOW CORNING CORPORATION (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5264603-A | Mixing a hydroxy endblocked polymer with hydrolyzable silane | DOW CORNING CORPORATION (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0560330-A2 | Substituted benzimidazolyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-09-15 | — | — | EP | disclosed |
| EP-0556789-A2 | Substituted biphenyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-08-25 | — | — | EP | disclosed |
| EP-0502314-A1 | Benzimidazol, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-09 | — | — | EP | disclosed |