SCHEMBL818329

SCHEMBL818329

CCC[N]C(=O)CCC.[KH]

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
HDAC3 O15379 4/20 0.39
HDAC1 Q13547 4/20 0.39
HDAC2 Q92769 4/20 0.39
HDAC8 Q9BY41 4/20 0.39
FFAR3 O14843 3/20 0.39
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.36
HDAC6 Q9UBN7 1/20 0.35
CTSD P07339 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL840682 0.97
SCHEMBL817979 0.95 CES2 (0.41) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL1086960 0.95 CES2 (0.41) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL818629 0.95 CES2 (0.41) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL840804 0.82 CES1 (0.48) CES2CES1TSHRALDH1A1
SCHEMBL7310066 0.82 CES1 (0.42) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL817947 0.81
SCHEMBL7312236 0.80 CES2 (0.44) CES2CES1TSHRALDH1A1
SCHEMBL4525864 0.80
SCHEMBL7300032 0.80 CES2 (0.50) CES2CES1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153545-B2 Process for homo—or copolymerization of conjugated olefins STYRON EUROPE GMBH (CH) 2012-04-10 US disclosed
US-20110160041-A1 PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS STYRON EUROPE GMBH 2011-06-30 US disclosed
US-7915194-B2 Process for homo- or copolymerization of conjugated olefins STYRON EUROPE GMBH (CH) 2011-03-29 US disclosed
US-20100248947-A1 PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-09-30 US disclosed
US-7612009-B2 Process for homo-or copolymerization of conjugated olefines DOW GLOBAL TECHNOLOGIES, INC. (US) 2009-11-03 US disclosed
US-20060142145-A1 Process for homo-or copolymerization of conjugated olefines TRINSEO EUROPE GMBH (CH) 2006-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110160041-A1 PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS F12, ETFB, F2 CES2 2896/4885CES1 2847/4885HDAC3 4579/4885
US-20060142145-A1 Process for homo-or copolymerization of conjugated olefines ETFB, F12, F2 CES2 2740/4885CES1 3019/4885HDAC3 4620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.