Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436686 | 0.76 | ADRB2 (0.37) | — | |
| SCHEMBL6062111 | 0.73 | — | — | |
| SCHEMBL30816821 | 0.73 | SMN1; SMN2 (0.35) | KDM4E | |
| Hydrochloric Acid SCHEMBL3719555 | 0.71 | — | — | |
| Cyclohexane SCHEMBL4856550 | 0.71 | KDM4E (0.46) | KDM4E | |
| SCHEMBL15345297 | 0.70 | KDM4E (0.31) | KDM4E | |
| SCHEMBL19135 | 0.70 | LMNA (0.34) | — | |
| SCHEMBL20104747 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL3714910 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL27943822 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415818-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AS DYRK1A INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064361-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AS DYRK1A INHIBITORS | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |