Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.87 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183764 | 0.94 | SIRT2 (0.97) | SIRT2OPRM1OPRL1CHRM1GRIA1 | |
| SCHEMBL7183702 | 0.94 | SIRT2 (0.77) | SIRT2OPRM1OPRL1CHRM1GRIA1 | |
| SCHEMBL7183695 | 0.94 | SIRT2 (0.77) | SIRT2OPRM1OPRL1CHRM1GRIA1 | |
| SCHEMBL14486983 | 0.87 | SIRT2 (0.71) | SIRT2OPRM1OPRL1CHRM1DRD2 | |
| SCHEMBL14410171 | 0.87 | SIRT2 (0.71) | SIRT2OPRM1OPRL1CHRM1DRD2 | |
| SCHEMBL9395620 | 0.80 | SIRT2 (0.77) | SIRT2OPRM1OPRL1GRIA1GRIA2 | |
| SCHEMBL25291004 | 0.76 | OPRM1 (0.61) | SIRT2OPRM1CHRM1DRD2 | |
| SCHEMBL9974821 | 0.76 | OPRM1 (0.61) | SIRT2OPRM1CHRM1DRD2HTR1A | |
| SCHEMBL8349502 | 0.76 | OPRM1 (0.61) | SIRT2OPRM1OPRL1CHRM1PARP1 | |
| SCHEMBL26666399 | 0.76 | DRD2 (0.70) | OPRM1CHRM1DRD2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867277-A | Novel fused heterocyclyl-carbohydrazone acyldinitrile compounds and use thereof | 韩国科学技术研究院 | 2023-03-28 | — | — | CN | disclosed |