Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22632905 | 0.86 | ALK (0.40) | ALKHTR6PDE4APDE4BPDE4C | |
| SCHEMBL22632544 | 0.86 | ALK (0.36) | ALKHTR6PDE4APDE4BPDE4C | |
| SCHEMBL22632943 | 0.84 | HTR6 (0.34) | ALKHTR6SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29414834 | 0.84 | HTR6 (0.34) | ALKHTR6SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL22632661 | 0.84 | ALK (0.36) | ALKHTR6PDE4APDE4BPDE4C | |
| SCHEMBL29414674 | 0.83 | CD4 (0.42) | ALKHTR6HTTCYP19A1 | |
| SCHEMBL22632610 | 0.83 | CD4 (0.42) | ALKHTR6HTTCYP19A1 | |
| SCHEMBL29414672 | 0.83 | CD4 (0.42) | ALKHTR6HTTCYP19A1 | |
| SCHEMBL31405774 | 0.82 | HTR6 (0.36) | ALKHTR6PDE4APDE4BPDE4C | |
| SCHEMBL30349385 | 0.82 | ALK (0.38) | ALKHTR6PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4178672-A1 | MODULATORS OF THR-ß AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2023-05-17 | — | — | EP | disclosed |