Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 9/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30351630 | 0.93 | PARP1 (0.46) | PARP1CHRNB2CHRNA4 | |
| SCHEMBL30352100 | 0.84 | PARP1 (0.45) | PARP1CHRNB2CHRNA4IRAK4 | |
| SCHEMBL30352272 | 0.84 | PARP1 (0.44) | PARP1CHRNB4CHRNA3 | |
| SCHEMBL30351699 | 0.82 | PARP1 (0.47) | PARP1 | |
| SCHEMBL30351668 | 0.82 | PARP1 (0.41) | PARP1CHRNB2CHRNA4IRAK4 | |
| SCHEMBL30352021 | 0.82 | PARP1 (0.44) | PARP1 | |
| SCHEMBL30352004 | 0.81 | PARP1 (0.40) | PARP1CHRNB2CHRNA4IRAK4 | |
| SCHEMBL30351817 | 0.81 | PARP1 (0.47) | PARP1 | |
| SCHEMBL26132496 | 0.80 | CHRNB2 (0.36) | PARP1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL30352207 | 0.79 | PARP1 (0.40) | PARP1CHRNB2CHRNA4IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066350-A1 | CRBN E3 LIGASE LIGAND COMPOUND, PROTEIN DEGRADING AGENT DEVELOPED ON THE BASIS OF LIGAND COMPOUND, AND THEIR APPLICATIONS | 标新生物医药科技(上海)有限公司 | 2023-04-27 | — | — | WO | claimed |