Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 9/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 8/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 5/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30351393 | 0.93 | PARP1 (0.45) | PARP1CHRNB2CHRNA4 | |
| SCHEMBL30352021 | 0.84 | PARP1 (0.44) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30351817 | 0.84 | PARP1 (0.47) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30351514 | 0.84 | PARP1 (0.46) | PARP1CHRNB2CHRNA4HTR2BHTR3E | |
| SCHEMBL30352272 | 0.82 | PARP1 (0.44) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30351708 | 0.82 | PARP1 (0.41) | PARP1CHRNB2CHRNA4HTR2BHTR3E | |
| SCHEMBL30351699 | 0.81 | PARP1 (0.47) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30352409 | 0.81 | PARP1 (0.41) | PARP1CHRNB2CHRNA4HTR2BHTR3E | |
| SCHEMBL26132331 | 0.81 | CHRNB2 (0.34) | PARP1CHRNB2CHRNA4POLBMAPT | |
| SCHEMBL30352057 | 0.80 | PARP1 (0.41) | PARP1CHRNB2CHRNA4HTR2BHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066350-A1 | CRBN E3 LIGASE LIGAND COMPOUND, PROTEIN DEGRADING AGENT DEVELOPED ON THE BASIS OF LIGAND COMPOUND, AND THEIR APPLICATIONS | 标新生物医药科技(上海)有限公司 | 2023-04-27 | — | — | WO | claimed |