Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL6392774 | 0.98 | ESR1 (0.56) | ESR1ESR2CALM1CA2ALDH1A1 | |
| SCHEMBL27851130 | 0.98 | ESR1 (0.56) | ESR1ESR2CALM1CA2ALDH1A1 | |
| SCHEMBL28271380 | 0.94 | ESR1 (0.52) | ESR1ESR2CALM1CA2ALDH1A1 | |
| SCHEMBL1338713 | 0.87 | NR3C1 (0.44) | CALM1TAAR1L3MBTL1SIGMAR1TDP1 | |
| SCHEMBL17609119 | 0.87 | ESR1 (0.45) | ESR1ESR2CALM1CA2ALDH1A1 | |
| SCHEMBL2150982 | 0.86 | CALM1 (0.62) | ESR1ESR2CALM1CA2ALDH1A1 | |
| Phenol SCHEMBL28271382 | 0.85 | ESR1 (0.51) | ESR1ESR2CA2SLC6A2KDM4E | |
| SCHEMBL14380667 | 0.85 | CALM1 (0.60) | ESR1ESR2CALM1CA2ALDH1A1 | |
| SCHEMBL10405435 | 0.83 | ESR1 (0.62) | ESR1ESR2CALM1CA2ALDH1A1 | |
| SCHEMBL15114763 | 0.83 | ESR1 (0.50) | ESR1ESR2CALM1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 543 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12187911-B2 | Method for preparing water-soluble acrylic-modified phenolic-modified epoxy resin, water-soluble acrylic-modified phenolic-modified epoxy resin prepared thereby, and aqueous coating composition comprising same | SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) | 2025-01-07 | — | — | US | claimed |
| CN-119080589-A | Preparation method of p-methoxyethylphenol | 常州瑞明药业有限公司 | 2024-12-06 | — | — | CN | claimed |
| CN-119019231-A | Preparation method of p-methoxyethylphenol | 常州瑞明药业有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-116020438-B | Solid acid catalyst, preparation method thereof and application of solid acid catalyst in deprotection reaction of p-tert-butoxyphenethyl methyl ether | 山东普洛汉兴医药有限公司 | 2024-08-02 | — | — | CN | claimed |
| US-20240117213-A1 | METHOD FOR PREPARING WATER-SOLUBLE ACRYLIC-MODIFIED PHENOLIC-MODIFIED EPOXY RESIN, WATER-SOLUBLE ACRYLIC-MODIFIED PHENOLIC-MODIFIED EPOXY RESIN PREPARED THEREBY, AND AQUEOUS COATING COMPOSITION COMPRISING SAME | SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) | 2024-04-11 | — | — | US | claimed |
| CN-117209653-B | Three-chain-segment polymer dispersing agent, preparation method thereof and lithium manganese iron phosphate positive electrode slurry | 江苏一特新材料有限责任公司 | 2024-01-02 | — | — | CN | claimed |
| CN-117209653-A | Three-chain-segment polymer dispersing agent, preparation method thereof and lithium manganese iron phosphate positive electrode slurry | 江苏一特新材料有限责任公司 | 2023-12-12 | — | — | CN | claimed |
| CN-114702372-B | Method for preparing 4- (2-methoxyl) ethylphenol | 台州市前进化工有限公司 | 2022-12-16 | — | — | CN | claimed |
| CN-111018724-B | Metoprolol and preparation method thereof | 江西美晶科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-115304500-A | Method for synthesizing metoprolol impurity | 北京康派森医药科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| US-6252113-B1 | O-ETHERIFICATION OF P-(2-METHOXYETHYL)-PHENOL WITH AQUEOUS EPICHLOROHYDRIN, EVAPORATION OF EXCESS EPICHLOROHYDRIN, DISTILLATION, THEN AMINATION WITH ISOPROPYLAMINE TO YIELD METOPROLOL PRODUCT | ASTRAZENECA AB (SE) | 2001-06-26 | — | — | US | claimed |
| EP-0942899-A1 | MANUFACTURING PROCESS OF METOPROLOL | Astra Aktiebolag (SE) | 1999-09-22 | — | — | EP | claimed |
| WO-1998022426-A1 | NEW MANUFACTURING PROCESS OF METOPROLOL | ASTRA AKTIEBOLAG (SE) | 1998-05-28 | — | — | WO | claimed |
| EP-0339006-B1 | PROCESS FOR PREPARING S-METOPROLOL AND INTERMEDIATES THEREFOR | Astra Pharmaceutical Production AB (SE) | 1992-07-08 | — | — | EP | claimed |
| US-5107034-A | Bromination of 4-hydroxyacetophenone, treating with methoxide to produce alpha-methoxy-4-hydroxyacetophenone, reduction | HOECHST CELANESE CORPORATION (US) | 1992-04-21 | — | — | US | claimed |
| US-5082969-A | Industrial process for obtaining an aryloxypropanolamine | ESTEVE QUIMICA, S.A. (ES) | 1992-01-21 | — | — | US | claimed |
| EP-0449602-A1 | Method for producing 4-(2'-methoxyethyl) phenol | HOECHST CELANESE CORPORATION (US) | 1991-10-02 | — | — | EP | claimed |
| US-5034535-A | Multistage reaction with chloroformate ester and isopropylamino-1,2-propanediol for cyclization, sulfonation and etherification | ASTRA PHARMACEUTICAL PRODUCTION AKTIEBOLAG (SE) | 1991-07-23 | — | — | US | claimed |
| EP-0339006-A1 | Process for preparing S-metoprolol and intermediates therefor | Astra Pharmaceutical Production AB (SE) | 1989-10-25 | — | — | EP | claimed |
| EP-0041295-B1 | PROCESS FOR THE PREPARATION OF 1-ISOPROPYLAMINO-3-(4-(2-METHOXY-ETHYL)-PHENOXY)-2-PROPANOL | Aktiebolaget Hässle (SE) | 1984-01-04 | — | — | EP | claimed |