SCHEMBL3035191

SCHEMBL3035191

O=C(O)CN1CCOC(=O)C1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.52
GLA P06280 1/20 0.36
KDM4E B2RXH2 2/20 0.34
TSHR P16473 2/20 0.33
ALOX15 P16050 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 3/20 0.32
SLC6A9 P48067 1/20 0.32
ACE P12821 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17287341 0.96 HSD17B10 (0.53) HSD17B10GLAKDM4ETSHRALOX15
Ammonia Solution, Strong SCHEMBL5494411 0.86 HSD17B10 (0.44) HSD17B10KDM4ETSHRSMN1; SMN2ALDH1A1
SCHEMBL12534301 0.79 HSD17B10 (0.38) HSD17B10GLAKDM4ETSHRSMN1; SMN2
SCHEMBL3037700 0.76 GSK3A (0.42) TSHRLMNAALDH1A1
SCHEMBL13104001 0.75 HSD17B10 (0.43) HSD17B10KDM4ETSHRSMN1; SMN2ALDH1A1
SCHEMBL529016 0.75 HSD17B10 (0.43) HSD17B10KDM4ETSHRSMN1; SMN2ALDH1A1
SCHEMBL3042153 0.74 KDM4E (0.45) GLAKDM4ESMN1; SMN2LMNAALDH1A1
SCHEMBL1708734 0.74
SCHEMBL7289691 0.74
SCHEMBL28280267 0.73 HSD17B10 (0.39) HSD17B10KDM4ESMN1; SMN2ALDH1A1SLC6A9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651237-A4 METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS JOHNSON & JOHNSON CONSUMER (US) 2008-10-01 EP claimed
EP-1651237-A2 METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS Galileo Pharmaceuticals, Inc. (US) 2006-05-03 EP claimed
WO-2005016270-A2 METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS GALILEO PHARMACEUTICALS, INC. (US) 2005-02-24 WO claimed
US-20050032751-A1 Methods for treatment of dermatological conditions JOHNSON & JOHNSON CONSUMER INC. 2005-02-10 US claimed
US-20230266675-A1 INSPECTION METHOD, METHOD FOR PRODUCING COMPOSITION, AND METHOD FOR VERIFYING COMPOSITION FUJIFILM CORPORATION (JP) 2023-08-24 US disclosed
US-20230266675-A1 INSPECTION METHOD, METHOD FOR PRODUCING COMPOSITION, AND METHOD FOR VERIFYING COMPOSITION FUJIFILM CORPORATION (JP) 2023-08-24 US disclosed
US-11703758-B2 Photosensitive composition for EUV light, pattern forming method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2023-07-18 US disclosed
US-11703758-B2 Photosensitive composition for EUV light, pattern forming method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2023-07-18 US disclosed
WO-2021241292-A1 ACTIVE-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTIVE-RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMATION METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE 富士フイルム株式会社 2021-12-02 WO disclosed
WO-2021065450-A1 ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR PRODUCING ELECTRONIC DEVICE 富士フイルム株式会社 2021-04-08 WO disclosed
US-20210011377-A1 PHOTOSENSITIVE COMPOSITION FOR EUV LIGHT, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2021-01-14 US disclosed
EP-3341007-B1 MALT1 INHIBITORS AND USES THEREOF UNIV CORNELL (US) 2020-12-23 EP disclosed
WO-2017040304-A1 MALT1 INHIBITORS AND USES THEREOF CORNELL UNIVERSITY (US) 2017-03-09 WO disclosed
EP-1651237-B1 METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS JOHNSON & JOHNSON CONSUMER (US) 2012-09-19 EP disclosed
US-20100202989-A1 METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS WANG BING 2010-08-12 US disclosed
US-7737179-B2 Methods for treatment of dermatological conditions J&J CONSUMER COMPANIES, INC. (US) 2010-06-15 US disclosed
EP-1651237-A4 METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS JOHNSON & JOHNSON CONSUMER (US) 2008-10-01 EP disclosed
EP-1651237-A2 METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS Galileo Pharmaceuticals, Inc. (US) 2006-05-03 EP disclosed
WO-2005016270-A2 METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS GALILEO PHARMACEUTICALS, INC. (US) 2005-02-24 WO disclosed
US-20050032751-A1 Methods for treatment of dermatological conditions JOHNSON & JOHNSON CONSUMER INC. 2005-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100202989-A1 METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS KRT18, CUTA, TUBB1 HSD17B10 421/4885GLA 19/4885KDM4E 1588/4885
US-20050032751-A1 Methods for treatment of dermatological conditions KRT18, CUTA, TUBB1 HSD17B10 421/4885GLA 19/4885KDM4E 1588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.