Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104001 | 0.86 | HSD17B10 (0.43) | HSD17B10TSHRMEN1GSK3AGSK3B | |
| SCHEMBL4266296 | 0.82 | HSD17B10 (0.46) | HSD17B10TSHR | |
| Ammonia Solution, Strong SCHEMBL5494411 | 0.81 | HSD17B10 (0.44) | HSD17B10TSHRMEN1GSK3AGSK3B | |
| SCHEMBL3035191 | 0.75 | HSD17B10 (0.52) | HSD17B10TSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5945932 | 0.73 | PTGS1 (0.42) | HSD17B10TSHRMEN1GSK3AGSK3B | |
| SCHEMBL17287341 | 0.72 | HSD17B10 (0.53) | HSD17B10TSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13800448 | 0.72 | TSHR (0.40) | TSHR | |
| SCHEMBL126833 | 0.72 | TSHR (0.40) | TSHR | |
| SCHEMBL28280267 | 0.71 | HSD17B10 (0.39) | HSD17B10KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2809739 | 0.71 | TDP1 (0.43) | HSD17B10TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535026-B | Method for synthesizing tetraalkyl nitrilo acetic acid diacetyl amide compound | 国立研究开发法人日本原子力研究开发机构 | 2021-10-29 | — | — | CN | claimed |
| CN-109021500-B | Epoxy resin glass fiber reinforced plastic for four-wheel electric vehicle shell | 安徽佳龙车业有限公司 | 2021-04-09 | — | — | CN | claimed |
| US-10259794-B2 | Methods for preparing fused bicyclic 2, 4-diaminopyrimidine derivatives | CEPHALON, INC. (US) | 2019-04-16 | — | — | US | claimed |
| US-20190092718-A1 | METHOD FOR SYNTHESIZING TETRAALKYLNITRILOACETIC ACID DIACETAMIDE COMPOUND | JAPAN ATOMIC ENERGY AGENCY (JP) | 2019-03-28 | — | — | US | claimed |
| US-20170369451-A1 | METHODS FOR PREPARING FUSED BICYCLIC 2, 4-DIAMINOPYRIMIDINE DERIVATIVES | CEPHALON, INC. | 2017-12-28 | — | — | US | claimed |
| EP-3237408-A1 | METHODS FOR PREPARING FUSED BICYCLIC 2, 4-DIAMINOPYRIMIDINE DERIVATIVES | Cephalon, Inc. (US) | 2017-11-01 | — | — | EP | claimed |
| WO-2016105529-A1 | METHODS FOR PREPARING FUSED BICYCLIC 2, 4-DIAMINOPYRIMIDINE DERIVATIVES | CEPHALON, INC. (US) | 2016-06-30 | — | — | WO | claimed |
| CN-103877947-B | The preparation method of a kind of high efficiency corn straw adsorbent and application thereof | 湖南大学 | 2016-06-08 | — | — | CN | claimed |
| US-20130190475-A1 | DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | SMARTCELLS, INC. (US) | 2013-07-25 | — | — | US | claimed |
| EP-2598170-A2 | DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | Smartcells, Inc. (US) | 2013-06-05 | — | — | EP | claimed |
| US-6872317-B1 | Chelate-forming filter, process for producing the same, and method of purifying liquid using the filter | CHELEST CORPORATION AND CHUBU CHELEST CO., LTD. (JP) | 2005-03-29 | — | — | US | claimed |
| EP-1090668-B1 | CHELATE-FORMING FILTER, PROCESS FOR PRODUCING THE SAME | CHELEST CORP (JP) | 2004-07-28 | — | — | EP | claimed |
| EP-0962582-B1 | METAL CHELATE FORMING FIBER, PROCESS FOR PREPARING THE SAME, AND METHOD OF METAL ION SEQUESTRATION USING SAID FIBER | CHELEST CORP (JP) | 2003-09-24 | — | — | EP | claimed |
| EP-1043316-B1 | Nitroimidazole derivatives as sensitivity enhancers for chemotherapy and radiotherapy | S & H PHARM TECHNOLOGY CO LTD (CN) | 2002-10-16 | — | — | EP | claimed |
| US-6271250-B1 | Metal Glycididaagolc, and preparation and uses thereof | S&H PHARM TECHNOLOGY CO., LTD (CN) | 2001-08-07 | — | — | US | claimed |
| EP-1090668-A1 | CHELATE-FORMING FILTER, PROCESS FOR PRODUCING THE SAME, AND METHOD OF PURIFYING LIQUID WITH THE FILTER | Chelest Corporation (JP) | 2001-04-11 | — | — | EP | claimed |
| US-6156075-A | WATER TREATMENT AND POLLUTION CONTROL | CHELEST CORPORATION (JP) | 2000-12-05 | — | — | US | claimed |
| EP-1043316-A2 | Nitroimidazole derivatives as sensitivity enhancers for chemotherapy and radiotherapy | S & H Pharm Technology Co. Ltd (CN) | 2000-10-11 | — | — | EP | claimed |
| EP-0962582-A1 | METAL CHELATE FORMING FIBER, PROCESS FOR PREPARING THE SAME, AND METHOD OF METAL ION SEQUESTRATION USING SAID FIBER | Chelest Corporation (JP) | 1999-12-08 | — | — | EP | claimed |
| EP-0107292-B1 | TC99M-PHENIDA, RADIOSCINTIGRAPHIC AGENT FOR DIAGNOSIS OF HEPATOBILIARY DISEASE | MERCK FROSST CANADA INC. (CA) | 1986-08-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369451-A1 | METHODS FOR PREPARING FUSED BICYCLIC 2, 4-DIAMINOPYRIMIDINE DERIVATIVES | DPYD, LIG4, CEP170 | HSD17B10 3975/4885TSHR 4506/4885MEN1 1314/4885 |
| US-20130190475-A1 | DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | ALK, ACVR1, ACVRL1 | HSD17B10 1588/4885TSHR 1106/4885MEN1 1714/4885 |
| US-20190092718-A1 | METHOD FOR SYNTHESIZING TETRAALKYLNITRILOACETIC ACID DIACETAMIDE COMPOUND | AVPR2, NAAA, AVPR1A | HSD17B10 785/4885TSHR 605/4885MEN1 1546/4885 |
| US-10259794-B2 | Methods for preparing fused bicyclic 2, 4-diaminopyrimidine derivatives | DPYD, LIG4, CEP170 | HSD17B10 3975/4885TSHR 4506/4885MEN1 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.