Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | ERG | P11308 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554212 | 1.00 | TSHR (0.42) | TSHRNPSR1ALDH1A1HTTLMNA | |
| SCHEMBL25554066 | 0.93 | PIK3CA (0.42) | TSHRNPSR1ALDH1A1HTTLMNA | |
| SCHEMBL30353095 | 0.93 | PIK3CA (0.42) | TSHRNPSR1ALDH1A1HTTLMNA | |
| SCHEMBL30353124 | 0.90 | ALDH1A1 (0.41) | TSHRNPSR1ALDH1A1HTTLMNA | |
| SCHEMBL25554226 | 0.90 | ALDH1A1 (0.41) | TSHRNPSR1ALDH1A1HTTLMNA | |
| SCHEMBL25058564 | 0.89 | CYP19A1 (0.36) | TSHRNPSR1ALDH1A1HTTLMNA | |
| SCHEMBL25554594 | 0.88 | SCN7A (0.34) | TSHRNPSR1ALDH1A1HTTLMNA | |
| SCHEMBL25554612 | 0.88 | EP300 (0.35) | TSHRNPSR1ALDH1A1HTTLMNA | |
| SCHEMBL30353111 | 0.86 | PIK3CA (0.43) | TSHRNPSR1ALDH1A1HTTLMNA | |
| SCHEMBL25554350 | 0.86 | PIK3CA (0.43) | TSHRNPSR1ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |