Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.42 |
| ▸ | AKT1 | P31749 | 5/20 | 0.42 |
| ▸ | MTOR | P42345 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 6/20 | 0.38 |
| ▸ | KIT | P10721 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.36 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554066 | 1.00 | PIK3CA (0.42) | PIK3CAAKT1MTORLMNACSF1R | |
| SCHEMBL25554350 | 0.94 | PIK3CA (0.43) | PIK3CAAKT1MTORLMNACSF1R | |
| SCHEMBL30353111 | 0.94 | PIK3CA (0.43) | PIK3CAAKT1MTORLMNACSF1R | |
| SCHEMBL30353087 | 0.93 | TSHR (0.42) | PIK3CAAKT1MTORLMNACSF1R | |
| SCHEMBL25554212 | 0.93 | TSHR (0.42) | PIK3CAAKT1MTORLMNACSF1R | |
| SCHEMBL23949247 | 0.90 | LMNA (0.42) | PIK3CAAKT1MTORLMNACSF1R | |
| SCHEMBL30256596 | 0.90 | LMNA (0.42) | PIK3CAAKT1MTORLMNACSF1R | |
| SCHEMBL25554524 | 0.89 | CDK7 (0.47) | PIK3CAAKT1MTORLMNACSF1R | |
| SCHEMBL25554357 | 0.89 | PIK3CA (0.41) | PIK3CAAKT1MTORLMNACSF1R | |
| SCHEMBL30256664 | 0.89 | PIK3CA (0.41) | PIK3CAAKT1MTORLMNACSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |