Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 4/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 3/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554088 | 1.00 | NSD2 (0.37) | NSD2ALOX5APFEN1GRM5KDM4E | |
| SCHEMBL25554071 | 0.92 | CYP11B1 (0.40) | NSD2ALOX5APFEN1GRM5KDM4E | |
| SCHEMBL30353086 | 0.92 | CYP11B1 (0.40) | NSD2ALOX5APFEN1GRM5KDM4E | |
| SCHEMBL30353104 | 0.91 | GRM5 (0.38) | NSD2ALOX5APFEN1GRM5CYP11B1 | |
| SCHEMBL25554119 | 0.91 | GRM5 (0.38) | NSD2ALOX5APFEN1GRM5CYP11B1 | |
| SCHEMBL25554052 | 0.90 | CYP11B2 (0.41) | NSD2ALOX5APFEN1GRM5KDM4E | |
| SCHEMBL25554077 | 0.86 | CYP11B2 (0.47) | KDM4EALDH1A1GAACYP11B1CYP19A1 | |
| SCHEMBL30257418 | 0.86 | NPC1 (0.36) | NSD2GRM5POLBCYP11B1CYP19A1 | |
| SCHEMBL25554706 | 0.86 | CYP11B1 (0.36) | NSD2ALOX5APFEN1GRM5CYP11B1 | |
| SCHEMBL25554084 | 0.86 | NPC1 (0.36) | NSD2GRM5POLBCYP11B1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |