Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.38 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.38 |
| ▸ | USP14 | P54578 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17922634 | 1.00 | CYP4F2 (0.46) | CYP4F2CYP4A11CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL17922652 | 0.81 | ALDH1A1 (0.56) | CYP4F2CYP4A11CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL30353266 | 0.81 | ALDH1A1 (0.56) | CYP4F2CYP4A11CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL7412851 | 0.80 | FFAR1 (0.47) | SMN1; SMN2KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL21824179 | 0.80 | CYP4F2 (0.49) | CYP4F2CYP4A11CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL8466268 | 0.79 | CYP4Z1 (0.54) | CYP4F2CYP4A11CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL7580544 | 0.79 | CYP4F2 (0.54) | CYP4F2CYP4A11CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL21824092 | 0.78 | CYP4F2 (0.55) | CYP4F2CYP4A11CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL19175675 | 0.78 | TSHR (0.42) | TLR8TLR7KDM4EALDH1A1MAPT | |
| SCHEMBL4270902 | 0.77 | CYP4F2 (0.64) | CYP4F2CYP4A11CYP1A2SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111039916-B | Tricyclic spiro compounds | 小野药品工业株式会社 | 2023-04-28 | — | — | CN | disclosed |