SCHEMBL30354331

SCHEMBL30354331

COC(=O)C1=COCN=C1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.34
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA7 P43166 3/20 0.34
CA9 Q16790 3/20 0.34
CA14 Q9ULX7 3/20 0.34
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.31
TRPA1 O75762 5/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPK1 P28482 2/20 0.30
HTT P42858 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27820145 0.68 CHRM3 (0.37) NPSR1CA12CA1CA2CA7
SCHEMBL6685416 0.68 NPSR1 (0.35) NPSR1CA12CA1CA2CA7
SCHEMBL28709250 0.68 CHRM3 (0.33) NPSR1CA12CA1CA2CA7
SCHEMBL5902597 0.64
SCHEMBL11596428 0.63
SCHEMBL30112181 0.63 NPSR1 (0.34) NPSR1CA12CA1CA2CA7
SCHEMBL2906792 0.63
SCHEMBL20909482 0.62 ALDH1A1 (0.55) NPSR1KDM4EALDH1A1TSHRMAPK1
SCHEMBL28610752 0.60 CHRM3 (0.36) NPSR1CA12CA1CA2CA7
SCHEMBL27990184 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115836059-A Process for the preparation of isoindolinone derivatives, novel intermediates used therein and process for the preparation thereof 忠北大学校产学协力团 2023-03-21 CN disclosed