Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428098 | 0.78 | — | — | |
| SCHEMBL14472183 | 0.73 | CHRM3 (0.33) | NPSR1MAPK1TSHRCHRM3KDM4E | |
| SCHEMBL23496634 | 0.68 | CHRM3 (0.36) | NPSR1MAPK1TSHRCHRM3CA12 | |
| SCHEMBL30354331 | 0.68 | NPSR1 (0.34) | NPSR1MAPK1TSHRKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL22634307 | 0.67 | KDM4E (0.35) | NPSR1MAPK1TSHRCHRM3KDM4E | |
| SCHEMBL19067575 | 0.66 | NOTUM (0.35) | MAPK1TSHRCHRM3KDM4EALDH1A1 | |
| SCHEMBL14816564 | 0.63 | TSHR (0.34) | NPSR1MAPK1TSHRKDM4EALDH1A1 | |
| SCHEMBL12502801 | 0.62 | SLC6A3 (0.42) | TSHRCHRM3ALDH1A1 | |
| SCHEMBL20599624 | 0.61 | NPSR1 (0.35) | NPSR1MAPK1TSHRCHRM3KDM4E | |
| SCHEMBL6021710 | 0.61 | KDM4E (0.33) | NPSR1MAPK1TSHRCHRM3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109640980-A | Combination and method comprising shell assembly inhibitor | 诺维拉治疗公司 | 2019-04-16 | — | — | CN | disclosed |
| WO-2004064774-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-08-05 | — | — | WO | disclosed |