Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991080 | 1.00 | FOLH1 (0.61) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL849666 | 0.90 | BCL2 (0.59) | FOLH1MRGPRX4 | |
| SCHEMBL3387825 | 0.89 | FOLH1 (0.58) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL31124111 | 0.89 | FOLH1 (0.58) | FOLH1MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL371526 | 0.88 | FOLH1 (0.70) | FOLH1MRGPRX4KMT2ACYP2D6CYP2C9 | |
| SCHEMBL443913 | 0.87 | RARB (0.58) | FOLH1KMT2A | |
| SCHEMBL11752450 | 0.86 | KAT6A (0.52) | FOLH1KAT6A | |
| SCHEMBL15766204 | 0.86 | RARB (0.59) | KMT2A | |
| SCHEMBL1876486 | 0.86 | RARB (0.59) | KMT2A | |
| SCHEMBL15174619 | 0.86 | RARB (0.59) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785752-B1 | INTERNAL ELECTRON DONOR FOR OLEFIN POLYMERIZATION CATALYSTS, METHOD OF MAKING AND USING THE SAME | BRASKEM AMERICA INC (US) | 2023-05-31 | — | — | EP | claimed |
| CN-112759672-B | Solid catalyst component for olefin polymerization, catalyst and application thereof | 中国石油化工股份有限公司 | 2023-04-11 | — | — | CN | claimed |