SCHEMBL849666

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28369070	0.90	BCL2 (0.56)	BCL2KMONR4A2LTB4R2PTPN11
	SCHEMBL991080	0.90	FOLH1 (0.61)	FOLH1MRGPRX4
	SCHEMBL30354557	0.90	FOLH1 (0.61)	FOLH1MRGPRX4
	SCHEMBL850998	0.89	KMO (0.61)	BCL2KMOLTB4R2PPARGPTPN11
	SCHEMBL12894987	0.86	BCL2 (0.78)	BCL2KMONR4A2RXRARXRB
	SCHEMBL13554034	0.83	CYP4F2 (0.63)	BCL2DHFRFNTAFNTBPGGT1B
	SCHEMBL30777855	0.82	CTSS (0.51)	BCL2
	SCHEMBL196298	0.82	CTSS (0.51)	BCL2
	SCHEMBL5519447	0.81	KMO (0.63)	BCL2KMONR4A2RXRARXRB
	SCHEMBL4533749	0.80	AGXT (0.52)	BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.