SCHEMBL30355083

SCHEMBL30355083

c1ccc2c(c1)-c1ccccc1[Si]21c2ccccc2-c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
CDC25B P30305 2/20 0.37
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 3/20 0.35
NPC1 O15118 2/20 0.35
MAOA P21397 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
APAF1 O14727 2/20 0.35
TDP2 O95551 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CES2 O00748 1/20 0.35
TERT O14746 1/20 0.35
PLIN1 O60240 1/20 0.35
S1PR4 O95977 1/20 0.35
LMNA P02545 1/20 0.35
PLA2G1B P04054 1/20 0.35
BCHE P06276 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240972 1.00 MEN1 (0.37) MEN1KMT2ACDC25BALDH1A1MAPK1
SCHEMBL24120875 0.97 MEN1 (0.40) MEN1KMT2ACDC25BALDH1A1MAPK1
SCHEMBL24120853 0.97 MEN1 (0.40) MEN1KMT2ACDC25BALDH1A1MAPK1
SCHEMBL11990882 0.84 RORA (0.41) RORARORC
SCHEMBL6255341 0.82 MEN1 (0.30) MEN1KMT2ACDC25BTHRBTDP1
SCHEMBL31424212 0.82 MEN1 (0.30) MEN1KMT2ACDC25BTHRBTDP1
SCHEMBL15164529 0.82 ALDH1A1 (0.42) ALDH1A1MAPK1MAOAL3MBTL1THRB
SCHEMBL30996984 0.82 MAPK1 (0.39) MAPK1MAOAKDM4ETSHRALOX15
SCHEMBL30996985 0.82 ALDH1A1 (0.39) MEN1KMT2AALDH1A1MAOAL3MBTL1
SCHEMBL7885315 0.82 MAPK1 (0.39) MAPK1MAOAKDM4ETSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113173945-B Method for constructing organic phase electrochemical luminescence system of rigid spirocyclic silole compound 西北师范大学 2023-04-07 CN claimed
CN-113173945-B Method for constructing organic phase electrochemical luminescence system of rigid spirocyclic silole compound 西北师范大学 2023-04-07 CN disclosed