⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15366515 | 0.83 | — | — | |
| SCHEMBL597386 | 0.82 | — | — | |
| SCHEMBL28152344 | 0.78 | — | — | |
| SCHEMBL6802366 | 0.78 | — | — | |
| SCHEMBL27472 | 0.78 | — | — | |
| SCHEMBL2254690 | 0.77 | L3MBTL1 (0.44) | — | |
| SCHEMBL1384461 | 0.75 | TAAR1 (0.43) | — | |
| SCHEMBL17103270 | 0.72 | — | — | |
| SCHEMBL28059343 | 0.69 | MEN1 (0.31) | — | |
| SCHEMBL17387743 | 0.69 | VDR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101505803-B | Composition for diagnosing amyloid-related disease | UNIV NAGASAKI | 2011-07-20 | — | — | CN | disclosed |
| US-20100278733-A1 | COMPOSITION FOR DIAGNOSIS OF AMYLOID-RELATED DISEASE | NAGASAKI UNIVERSITY (JP) | 2010-11-04 | — | — | US | disclosed |
| CN-101505803-A | Composition for diagnosing amyloid-related disease | UNIV NAGASAKI (JP) | 2009-08-12 | — | — | CN | disclosed |
| EP-2030635-A1 | COMPOSITION FOR DIAGNOSING AMYLOID-RELATED DISEASE | Nagasaki University (JP) | 2009-03-04 | — | — | EP | disclosed |