Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893061 | 1.00 | IGF1R (0.46) | IGF1RALDH1A1SMN1; SMN2KMT2ATP53 | |
| SCHEMBL8646992 | 0.86 | GAA (0.40) | KMT2ASLC6A4SLC6A3BRD4MEN1 | |
| SCHEMBL7335768 | 0.83 | ALDH1A1 (0.51) | IGF1RALDH1A1SMN1; SMN2TP53CYP1A2 | |
| SCHEMBL30357998 | 0.83 | IGF1R (0.46) | IGF1RALDH1A1SMN1; SMN2KMT2ATP53 | |
| SCHEMBL30358032 | 0.83 | ALDH1A1 (0.51) | IGF1RALDH1A1SMN1; SMN2TP53CYP1A2 | |
| SCHEMBL30358011 | 0.83 | IGF1R (0.46) | IGF1RALDH1A1SMN1; SMN2KMT2ATP53 | |
| SCHEMBL7433964 | 0.80 | SMYD3 (0.56) | IGF1RALDH1A1KMT2ACYP1A2HPGD | |
| SCHEMBL926907 | 0.80 | SMYD3 (0.56) | IGF1RALDH1A1KMT2ACYP1A2HPGD | |
| SCHEMBL30357995 | 0.80 | SMYD3 (0.56) | IGF1RALDH1A1KMT2ACYP1A2HPGD | |
| SCHEMBL8567081 | 0.80 | SMYD3 (0.56) | IGF1RALDH1A1KMT2ACYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872820-B | Method for synthesizing chiral 2-functionalized tetrahydroquinoline through biomimetic catalysis and asymmetric hydrogenation | 中国科学院大连化学物理研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115872820-A | Method for synthesizing chiral 2-functional group tetrahydroquinoline by biomimetic catalytic asymmetric hydrogenation | 中国科学院大连化学物理研究所 | 2023-03-31 | — | — | CN | disclosed |