Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 1.00 |
| ▸ | ALDH1A2 | O94788 | 7/20 | 1.00 |
| ▸ | ALDH1A3 | P47895 | 7/20 | 1.00 |
| ▸ | TP53 | P04637 | 7/20 | 0.84 |
| ▸ | LMNA | P02545 | 5/20 | 0.84 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19748997 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALDH1A2ALDH1A3TP53LMNA | |
| SCHEMBL30358101 | 0.86 | ALDH1A1 (1.00) | ALDH1A1ALDH1A2ALDH1A3TP53LMNA | |
| SCHEMBL29522912 | 0.86 | ALDH1A1 (1.00) | ALDH1A1ALDH1A2ALDH1A3TP53LMNA | |
| SCHEMBL17208552 | 0.86 | ALDH1A1 (1.00) | ALDH1A1ALDH1A2ALDH1A3TP53LMNA | |
| SCHEMBL26978056 | 0.85 | ALDH1A1 (0.74) | ALDH1A1ALDH1A2ALDH1A3TP53LMNA | |
| SCHEMBL19745710 | 0.80 | ALDH1A3 (1.00) | ALDH1A1ALDH1A2ALDH1A3TP53LMNA | |
| SCHEMBL30358099 | 0.80 | ALDH1A3 (1.00) | ALDH1A1ALDH1A2ALDH1A3TP53LMNA | |
| SCHEMBL30358120 | 0.79 | ALDH1A1 (1.00) | ALDH1A1ALDH1A2ALDH1A3 | |
| SCHEMBL19746114 | 0.79 | ALDH1A1 (1.00) | ALDH1A1ALDH1A2ALDH1A3 | |
| SCHEMBL19745931 | 0.78 | ALDH1A3 (0.82) | ALDH1A1ALDH1A2ALDH1A3TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059884-A1 | ALDH INHIBITORS TO PROMOTE IMMUNE CELL EXPANSION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-04-13 | — | — | WO | claimed |
| WO-2023059884-A1 | ALDH INHIBITORS TO PROMOTE IMMUNE CELL EXPANSION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-04-13 | — | — | WO | disclosed |