SCHEMBL30358374

SCHEMBL30358374

CC(C)[C@H](NC(=O)CN)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O)C(C)C

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 4/20 0.45
▸ ACE P12821 9/20 0.44
▸ KDM4E B2RXH2 1/20 0.43
▸ F2 P00734 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ LTA4H P09960 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ PEPD P12955 1/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ PTGS1 P23219 1/20 0.43
▸ HTR2A P28223 1/20 0.43
▸ PTGS2 P35354 1/20 0.43
▸ HRH1 P35367 1/20 0.43
▸ THPO P40225 1/20 0.43
▸ PMP22 Q01453 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ ACE2 Q9BYF1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29966881 0.97 REN (0.46) RENACEKDM4EF2LMNA
SCHEMBL30263777 0.94 REN (0.50) RENACEKDM4EF2LMNA
SCHEMBL28101347 0.93 REN (0.47) RENACEKDM4EF2LMNA
SCHEMBL5025979 0.93 REN (0.47) RENACEKDM4EF2LMNA
SCHEMBL5025984 0.93 REN (0.47) RENACEKDM4EF2LMNA
SCHEMBL31721732 0.89 ACE (0.36) RENACEKDM4EF2LMNA
SCHEMBL30558184 0.88 XIAP (0.43) RENACEF2
SCHEMBL31316110 0.86 REN (0.47) RENACEKDM4EF2LMNA
SCHEMBL31615113 0.85 XIAP (0.44) RENACEF2
SCHEMBL29790196 0.83 REN (0.55) RENACEKDM4EF2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240165299-A1 TISSUE SCAFFOLD RAFT ENTERPRISES LIMITED (GB) 2024-05-23 — — US disclosed
EP-4338764-A2 TISSUE SCAFFOLD Raft Enterprises Ltd. (GB) 2024-03-20 — — EP disclosed
US-11738112-B2 Tissue scaffold RAFT ENTERPRISES LIMITED (GB) 2023-08-29 — — US disclosed
EP-3651817-B1 TISSUE SCAFFOLD RAFT ENTPR LTD (GB) 2023-05-03 — — EP disclosed
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