SCHEMBL5025984

SCHEMBL5025984

CC(C)[C@H](NC(=O)CN)C(=O)NCC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 4/20 0.47
▸ ACE P12821 7/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ F2 P00734 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ LTA4H P09960 1/20 0.45
▸ MAPT P10636 1/20 0.45
▸ PEPD P12955 1/20 0.45
▸ ALOX15 P16050 1/20 0.45
▸ PTGS1 P23219 1/20 0.45
▸ HTR2A P28223 1/20 0.45
▸ PTGS2 P35354 1/20 0.45
▸ HRH1 P35367 1/20 0.45
▸ THPO P40225 1/20 0.45
▸ PMP22 Q01453 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ ACE2 Q9BYF1 1/20 0.45
▸ ELANE P08246 2/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28101347 1.00 REN (0.47) RENACEKDM4EF2LMNA
SCHEMBL5025979 1.00 REN (0.47) RENACEKDM4EF2LMNA
SCHEMBL29966881 0.94 REN (0.46) RENACEKDM4EF2LMNA
SCHEMBL30358374 0.93 REN (0.45) RENACEKDM4EF2LMNA
SCHEMBL29790196 0.91 REN (0.55) RENACEKDM4EF2LMNA
SCHEMBL29411311 0.90 REN (0.46) RENACEKDM4EF2LMNA
SCHEMBL29411300 0.90 ELANE (0.46) ACEELANE
SCHEMBL13567377 0.90 XIAP (0.44) F2ELANE
SCHEMBL11989026 0.89 ELANE (0.44) F2ELANE
SCHEMBL31316110 0.87 REN (0.47) RENACEKDM4EF2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240165299-A1 TISSUE SCAFFOLD RAFT ENTERPRISES LIMITED (GB) 2024-05-23 — — US disclosed
EP-4338764-A2 TISSUE SCAFFOLD Raft Enterprises Ltd. (GB) 2024-03-20 — — EP disclosed
US-11738112-B2 Tissue scaffold RAFT ENTERPRISES LIMITED (GB) 2023-08-29 — — US disclosed
US-20230218723-A1 COMPOSITIONS AND METHODS FOR USING SILK-ELASTINLIKE PROTEIN-BASED POLYMERS NATIONAL INSTITUTES OF HEALTH 2023-07-13 — — US disclosed
EP-3651817-B1 TISSUE SCAFFOLD RAFT ENTPR LTD (GB) 2023-05-03 — — EP disclosed
US-11337994-B2 In situ gelling compositions for the treatment or prevention of inflammation and tissue damage UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2022-05-24 — — US disclosed
CN-106083996-B Nutgall acyl peptide derivant and anti-aging Dermatologic preparation composition containing the derivative 生物FD&C株式会社 2019-10-01 — — CN disclosed
CN-106083996-A Galla Turcica (Galla Helepensis) acyl peptide derivant and the aging resistance Dermatologic preparation composition containing this derivant 生物FD&C株式会社 2016-11-09 — — CN disclosed
US-7329802-B1 Genetic engineering of cotton to increase fiber strength, water absorption and dye binding AUBURN UNIVERSITY 2008-02-12 — — US disclosed
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