Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 4/20 | 0.38 |
| ▸ | GABRD | O14764 | 4/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30358397 | 0.87 | GRK6 (0.42) | MAPTKDM4EPIK3CDPIK3CBNPC1 | |
| SCHEMBL30358389 | 0.82 | PIK3CG (0.51) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28319461 | 0.82 | KDM4E (0.68) | MAPTKDM4EPIK3CDPIK3CBNPC1 | |
| SCHEMBL16067280 | 0.79 | MAPT (0.50) | MAPTKDM4EPIK3CDPIK3CBNPC1 | |
| SCHEMBL5794092 | 0.79 | MAPT (0.46) | MAPTKDM4EPIK3CDPIK3CBNPC1 | |
| SCHEMBL19746823 | 0.79 | MAPT (0.46) | MAPTKDM4EPIK3CDPIK3CBNPC1 | |
| SCHEMBL28319423 | 0.77 | NPC1 (0.63) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28318330 | 0.77 | TTR (0.49) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30358381 | 0.77 | MGLL (0.41) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28318312 | 0.77 | MGLL (0.41) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105300-B | Method for synthesizing 2-trifluoroethyl substituted benzoxazole compound | 福州大学 | 2023-04-14 | — | — | CN | disclosed |