SCHEMBL30359052

SCHEMBL30359052

COc1ccc(Cl)c(C(=O)N2CC3CCC2CN3)n1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 19/20 0.48
KCNK9 Q9NPC2 19/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30359024 0.88 KCNK3 (0.46) KCNK3KCNK9
SCHEMBL30359021 0.88 KCNK3 (0.46) KCNK3KCNK9
SCHEMBL29432825 0.87 KCNK3 (0.47) KCNK3KCNK9
SCHEMBL22001581 0.83 KCNK3 (0.46) KCNK3KCNK9
SCHEMBL30359048 0.81 KCNK3 (0.45) KCNK3KCNK9
SCHEMBL30359062 0.78 KCNK3 (0.48) KCNK3KCNK9
SCHEMBL30359175 0.77 KCNK3 (0.49) KCNK3KCNK9
SCHEMBL21904724 0.74 KCNK3 (0.45) KCNK3KCNK9
SCHEMBL1176698 0.72 RBP4 (0.42)
SCHEMBL1383934 0.72 GSK3B (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116057057-A Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea 拜耳公司 2023-05-02 CN disclosed