Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 19/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 19/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21904724 | 0.93 | KCNK3 (0.45) | KCNK3KCNK9 | |
| SCHEMBL30359111 | 0.86 | HTR2A (0.41) | KCNK3KCNK9HTR2AHTR2CHTR2B | |
| SCHEMBL30359131 | 0.85 | KCNK3 (0.47) | KCNK3KCNK9HTR2AHTR2CHTR2B | |
| SCHEMBL22001581 | 0.84 | KCNK3 (0.46) | KCNK3KCNK9HTR2AHTR2CHTR2B | |
| SCHEMBL20587387 | 0.79 | KCNK3 (0.46) | KCNK3KCNK9 | |
| SCHEMBL30359095 | 0.79 | KCNK3 (0.46) | KCNK3KCNK9 | |
| SCHEMBL30359044 | 0.79 | HTR2A (0.41) | KCNK3KCNK9HTR2AHTR2CHTR2B | |
| SCHEMBL30359052 | 0.78 | KCNK3 (0.48) | KCNK3KCNK9 | |
| SCHEMBL30359079 | 0.77 | MGLL (0.47) | KCNK3KCNK9HTR2AHTR2CHTR2B | |
| SCHEMBL30359003 | 0.76 | HTR2A (0.42) | KCNK3KCNK9HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |