Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 17/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 17/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001648 | 0.93 | KCNK3 (0.45) | MGLLKCNK3KCNK9 | |
| SCHEMBL30359162 | 0.89 | MGLL (0.43) | MGLLKCNK3KCNK9HTR2AHTR2C | |
| SCHEMBL30359034 | 0.84 | MGLL (0.44) | MGLLKCNK3KCNK9HTR2AHTR2C | |
| SCHEMBL21904749 | 0.84 | KCNK3 (0.48) | MGLLKCNK3KCNK9 | |
| SCHEMBL30359027 | 0.83 | KCNK3 (0.49) | MGLLKCNK3KCNK9HTR2AHTR2C | |
| SCHEMBL22001486 | 0.83 | KCNK3 (0.49) | MGLLKCNK3KCNK9HTR2AHTR2C | |
| SCHEMBL20070578 | 0.79 | MGLL (0.45) | MGLLKCNK3KCNK9 | |
| SCHEMBL30359104 | 0.79 | KCNK3 (0.47) | KCNK3KCNK9 | |
| SCHEMBL30358990 | 0.79 | KCNK3 (0.46) | MGLLKCNK3KCNK9HTR2AHTR2C | |
| SCHEMBL20587815 | 0.78 | KCNK3 (0.51) | MGLLKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |