Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359019 | 0.92 | MEN1 (0.50) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL30359059 | 0.87 | MEN1 (0.43) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL20587811 | 0.84 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL30359130 | 0.84 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL30359107 | 0.78 | MEN1 (0.41) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL20589067 | 0.78 | KCNK3 (0.42) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL30359077 | 0.75 | ALDH1A1 (0.48) | KMT2AALDH1A1HTTCYP2C9CYP2C19 | |
| SCHEMBL30790488 | 0.75 | SLC6A4 (0.46) | ALOX15TSHRLMNA | |
| SCHEMBL30359010 | 0.73 | SLC6A2 (0.46) | ALDH1A1LMNA | |
| SCHEMBL10243703 | 0.73 | MEN1 (0.50) | MEN1KMT2AALDH1A1KDM4EHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |