Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359135 | 0.87 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL30359077 | 0.82 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL30359019 | 0.80 | MEN1 (0.50) | ALDH1A1LMNA | |
| SCHEMBL14172576 | 0.74 | CHRNB2 (0.56) | SLC6A4SLC6A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27153138 | 0.73 | CHRNB2 (0.54) | SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL30359152 | 0.73 | MEN1 (0.46) | ALDH1A1LMNA | |
| SCHEMBL20587811 | 0.72 | MEN1 (0.46) | ALDH1A1LMNA | |
| SCHEMBL30359130 | 0.72 | MEN1 (0.46) | ALDH1A1LMNA | |
| SCHEMBL30790612 | 0.72 | SLC6A4 (0.46) | SLC6A4SLC6A3LMNA | |
| SCHEMBL30359059 | 0.70 | MEN1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |