Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | MTTP | P55157 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541801 | 1.00 | FFAR4 (0.34) | FFAR4SYKDYRK1AMAP4K4NPY2R | |
| SCHEMBL30359448 | 0.92 | MELK (0.33) | FFAR4SYKDYRK1AWDR5 | |
| SCHEMBL21541807 | 0.92 | MELK (0.33) | FFAR4SYKDYRK1AWDR5 | |
| SCHEMBL29559929 | 0.91 | S1PR1 (0.33) | WDR5 | |
| SCHEMBL21541836 | 0.91 | S1PR1 (0.33) | WDR5 | |
| SCHEMBL21541719 | 0.88 | PRKDC (0.38) | WDR5 | |
| SCHEMBL30359438 | 0.88 | PRKDC (0.38) | WDR5 | |
| SCHEMBL21541749 | 0.87 | CSF1R (0.37) | FFAR4DYRK1AMAP4K4 | |
| SCHEMBL21541763 | 0.83 | CCNA2 (0.34) | WDR5 | |
| SCHEMBL29559089 | 0.83 | CCNA2 (0.34) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |