Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25230127 | 1.00 | MAP4K4 (0.38) | MAP4K4MAPK9CSNK1A1CSNK1DMINK1 | |
| SCHEMBL25206204 | 0.90 | MAPK14 (0.40) | MAP4K4KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL30359478 | 0.90 | MAPK14 (0.40) | MAP4K4KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL25205150 | 0.83 | MAPK1 (0.41) | MAP4K4KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL25238696 | 0.83 | ALDH1A1 (0.40) | MAP4K4PRKD3GSK3AGSK3BAURKB | |
| SCHEMBL30359461 | 0.83 | ALDH1A1 (0.40) | MAP4K4PRKD3GSK3AGSK3BAURKB | |
| SCHEMBL25206143 | 0.82 | KDM4E (0.38) | MAP4K4KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL30359474 | 0.82 | KDM4E (0.38) | MAP4K4KDM4ENPC1HCRTR1USP2 | |
| SCHEMBL25528944 | 0.81 | KDM4E (0.36) | MAP4K4MAPK9CSNK1A1CSNK1DMINK1 | |
| SCHEMBL25255165 | 0.80 | MAP4K4 (0.40) | MAP4K4KDM4ENPC1HCRTR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4433485-A1 | ADENOSINE RECEPTOR ANTAGONISTS | Crossignal Therapeutics, Inc. (US) | 2024-09-25 | — | — | EP | claimed |
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | claimed |
| EP-4433485-A1 | ADENOSINE RECEPTOR ANTAGONISTS | Crossignal Therapeutics, Inc. (US) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |