Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25238696 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPK1HSD17B10USP2TSHR | |
| SCHEMBL25206143 | 0.87 | KDM4E (0.38) | ALDH1A1MAPK1HSD17B10USP2TSHR | |
| SCHEMBL30359474 | 0.87 | KDM4E (0.38) | ALDH1A1MAPK1HSD17B10USP2TSHR | |
| SCHEMBL30359465 | 0.86 | TGFBR1 (0.41) | ALDH1A1MAPK1HSD17B10USP2TSHR | |
| SCHEMBL25209828 | 0.86 | TGFBR1 (0.41) | ALDH1A1MAPK1HSD17B10USP2TSHR | |
| SCHEMBL25231898 | 0.86 | MAP4K4 (0.42) | ALDH1A1MAPK1HSD17B10USP2TSHR | |
| SCHEMBL30359463 | 0.86 | MAP4K4 (0.42) | ALDH1A1MAPK1HSD17B10USP2TSHR | |
| SCHEMBL25205150 | 0.84 | MAPK1 (0.41) | ALDH1A1MAPK1HSD17B10USP2TSHR | |
| SCHEMBL25251378 | 0.83 | KDR (0.41) | ALDH1A1MAPK1HSD17B10USP2TSHR | |
| SCHEMBL30359460 | 0.83 | KDR (0.41) | ALDH1A1MAPK1HSD17B10USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4433485-A1 | ADENOSINE RECEPTOR ANTAGONISTS | Crossignal Therapeutics, Inc. (US) | 2024-09-25 | — | — | EP | claimed |
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | claimed |
| EP-4433485-A1 | ADENOSINE RECEPTOR ANTAGONISTS | Crossignal Therapeutics, Inc. (US) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |