Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 10/20 | 0.36 |
| ▸ | ATR | Q13535 | 10/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 10/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.36 |
| ▸ | ATM | Q13315 | 5/20 | 0.36 |
| ▸ | MTOR | P42345 | 6/20 | 0.35 |
| ▸ | SERPINA2 | P20848 | 5/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | NPM1 | P06748 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20374558 | 1.00 | SIGMAR1 (0.38) | SIGMAR1LMNAKMT2APRKDCATR | |
| SCHEMBL21541863 | 1.00 | SIGMAR1 (0.38) | SIGMAR1LMNAKMT2APRKDCATR | |
| SCHEMBL20374559 | 0.86 | PRKDC (0.37) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL21541858 | 0.86 | PRKDC (0.37) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL30359501 | 0.86 | PRKDC (0.37) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL2463549 | 0.80 | HTT (0.45) | PRKDCATRATRIPPIK3CBATM | |
| SCHEMBL21541888 | 0.74 | PTPN11 (0.39) | LMNAKMT2AMETPDE3BPDE3A | |
| SCHEMBL30359508 | 0.74 | PTPN11 (0.39) | LMNAKMT2AMETPDE3BPDE3A | |
| SCHEMBL797783 | 0.73 | NPM1 (0.42) | LMNAPRKDCATRATRIPPIK3CB | |
| SCHEMBL796862 | 0.71 | PRKDC (0.55) | PRKDCATRATRIPPIK3CBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |