Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 2/20 | 0.31 |
| ▸ | CCND1 | P24385 | 2/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541888 | 1.00 | PTPN11 (0.39) | PTPN11METPDE3BPDE3AHRH4 | |
| SCHEMBL21541873 | 0.86 | HRH4 (0.33) | HRH4CYP11B1CYP11B2KMT2A | |
| SCHEMBL30359522 | 0.86 | HRH4 (0.33) | HRH4CYP11B1CYP11B2KMT2A | |
| SCHEMBL21541863 | 0.74 | SIGMAR1 (0.38) | PTPN11METPDE3BPDE3AKMT2A | |
| SCHEMBL30359498 | 0.74 | SIGMAR1 (0.38) | PTPN11METPDE3BPDE3AKMT2A | |
| SCHEMBL20374558 | 0.74 | SIGMAR1 (0.38) | PTPN11METPDE3BPDE3AKMT2A | |
| SCHEMBL14901231 | 0.70 | PTPN11 (0.38) | PTPN11HRH4CHRNB4CHRNA3KMT2A | |
| SCHEMBL21541814 | 0.67 | PRKDC (0.58) | — | |
| SCHEMBL31104892 | 0.65 | CHRNB2 (0.66) | CHRNB4CHRNA3KMT2ACHRNB2CHRNA4 | |
| SCHEMBL10756477 | 0.65 | CHRNB2 (0.66) | CHRNB4CHRNA3KMT2ACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |