Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359560 | 1.00 | NNMT (0.47) | NNMTKDM4EMEN1MAPTKMT2A | |
| SCHEMBL22041870 | 1.00 | NNMT (0.47) | NNMTKDM4EMEN1MAPTKMT2A | |
| SCHEMBL30359552 | 0.89 | MEN1 (0.37) | NNMTKDM4EMEN1MAPTKMT2A | |
| SCHEMBL22041907 | 0.87 | NNMT (0.46) | NNMTKDM4EMEN1MAPTKMT2A | |
| SCHEMBL248031 | 0.86 | MEN1 (0.47) | NNMTKDM4EMEN1MAPTKMT2A | |
| SCHEMBL29974797 | 0.86 | MEN1 (0.47) | NNMTKDM4EMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL2307128 | 0.85 | MEN1 (0.46) | NNMTKDM4EMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL31459134 | 0.85 | MEN1 (0.46) | NNMTKDM4EMEN1MAPTKMT2A | |
| SCHEMBL22041887 | 0.81 | NNMT (0.51) | NNMTKDM4EMEN1MAPTKMT2A | |
| SCHEMBL23796992 | 0.80 | NNMT (0.50) | NNMTKDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285886-B | Substituted pyrazolo [1,5-a ] pyridine compounds, compositions comprising the same and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2023-04-11 | — | — | CN | disclosed |