SCHEMBL248031

SCHEMBL248031

COc1ccc(CCl)cn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
KDM1A O60341 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
NNMT P40261 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41
CYP11B1 P15538 1/20 0.41
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29974797 1.00 MEN1 (0.47) MEN1KMT2AKDM4EMAPTKDM1A
Hydrochloric Acid SCHEMBL31459134 0.98 MEN1 (0.46) MEN1KMT2AKDM4EMAPTKDM1A
Hydrochloric Acid SCHEMBL2307128 0.98 MEN1 (0.46) MEN1KMT2AKDM4EMAPTKDM1A
SCHEMBL22041870 0.86 NNMT (0.47) MEN1KMT2AKDM4EMAPTKDM1A
SCHEMBL30359560 0.86 NNMT (0.47) MEN1KMT2AKDM4EMAPTKDM1A
SCHEMBL30359558 0.86 NNMT (0.47) MEN1KMT2AKDM4EMAPTKDM1A
SCHEMBL30359552 0.86 MEN1 (0.37) MEN1KMT2AKDM4EMAPTKDM1A
SCHEMBL16797049 0.84 MEN1 (0.45) MEN1KMT2AKDM4EMAPTKDM1A
SCHEMBL22041830 0.84 MEN1 (0.45) MEN1KMT2AKDM4EMAPTKDM1A
SCHEMBL30359555 0.84 MEN1 (0.45) MEN1KMT2AKDM4EMAPTKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055016-B1 GPR52 MODULATOR COMPOUNDS NXERA PHARMA UK LTD (GB) 2026-04-29 EP disclosed
US-20260078123-A1 PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF SHANGHAI DAIDAI INVESTMENT CONSULTING CO., LTD (CN) 2026-03-19 US disclosed
EP-3704094-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-11 EP disclosed
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) SHANGHAI DEGRON BIOMEDICAL TECH CO LTD (CN) 2026-02-05 US disclosed
US-12516054-B2 Pyrazolo[1,5-a]pyridine derivatives, preparation method therefor and use thereof SHANGHAI DAIDAI INVESTMENT CONSULTING CO., LTD (CN) 2026-01-06 US disclosed
EP-4626880-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) Shanghai Degron Biomedical Technology Co., Ltd. (CN) 2025-10-08 EP disclosed
US-20250288595-A1 TROPOMYOSIN-RELATED KINASE (TRK) INHIBITORS GENZYME CORP (US) 2025-09-18 US disclosed
US-12318392-B2 Tropomyosin-related kinase (trk) inhibitors GENZYME CORPORATION (US) 2025-06-03 US disclosed
EP-4077306-B1 COMPOUNDS AND PROBES FOR IMAGING HUNTINGTIN PROTEIN CHDI FOUNDATION INC (US) 2025-05-07 EP disclosed
WO-2025085347-A1 IL4I1 INHIBITORS AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2025-04-24 WO disclosed
US-5173496-A Antiinflammatory agents ICI PHARMA (FR) 1992-12-22 US disclosed
EP-0284174-B1 THERAPEUTIC PREPARATIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-07-29 EP disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 US disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4812571-A NITROMETHYLENE COMPOUNDS NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-03-14 US disclosed
EP-0284174-A1 Therapeutic preparations IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-09-28 EP disclosed
US-4774247-A Nitromethylene derivative insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-09-27 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
US-4678795-A 1-pyridylmethyl-2-nitromethylene-1,3-diazacycloalkane insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1987-07-07 US disclosed
EP-0163855-A1 Nitromethylene derivatives, intermediates, and process for their preparation as insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078123-A1 PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF NR3C1, CXCR1, CCR1 MEN1 2204/4885KMT2A 2946/4885KDM4E 4419/4885
US-12318392-B2 Tropomyosin-related kinase (trk) inhibitors NTRK1, NGF, NTRK2 MEN1 2734/4885KMT2A 2861/4885KDM4E 3769/4885
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) ELAVL1, ELAVL3, HNRNPL MEN1 1990/4885KMT2A 3940/4885KDM4E 4185/4885
US-20250288595-A1 TROPOMYOSIN-RELATED KINASE (TRK) INHIBITORS NTRK1, NGF, NTRK2 MEN1 2734/4885KMT2A 2861/4885KDM4E 3769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.