Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.73 |
| ▸ | GAA | P10253 | 15/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077266 | 0.83 | MAPT (1.00) | MAPTGAAALDH1A1KDM4EHTT | |
| SCHEMBL2254038 | 0.77 | MAPT (0.67) | MAPTGAAALDH1A1KDM4EHTT | |
| SCHEMBL12781557 | 0.77 | GAA (0.88) | MAPTGAAALDH1A1KDM4EHTT | |
| SCHEMBL14016031 | 0.77 | MAPT (0.70) | MAPTGAAALDH1A1KDM4EHTT | |
| SCHEMBL2249852 | 0.77 | MAPT (0.70) | MAPTGAAALDH1A1KDM4EHTT | |
| SCHEMBL2254064 | 0.76 | MAPT (0.72) | MAPTGAAALDH1A1KDM4EHTT | |
| SCHEMBL2258152 | 0.76 | MAPT (0.72) | MAPTGAAALDH1A1KDM4EHTT | |
| SCHEMBL2249830 | 0.74 | MAPT (0.70) | MAPTGAAALDH1A1KDM4EHTT | |
| SCHEMBL2252221 | 0.74 | MAPT (0.69) | MAPTGAAALDH1A1KDM4EHTT | |
| SCHEMBL6651229 | 0.74 | GAA (0.71) | MAPTGAAALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240408072-A1 | COMPOSITION FOR PREVENTING OR TREATING GRAVES' DISEASE COMPRISING COMPOUND CONTAINING AN IMIDAZOPYRIDINE STRUCTURE AS ACTIVE INGREDIENT | ESGELBIO INC. (KR) | 2024-12-12 | — | — | US | disclosed |
| WO-2023075285-A1 | COMPOSITION FOR PREVENTING OR TREATING GRAVES' DISEASE COMPRISING COMPOUND CONTAINING AN IMIDAZOPYRIDINE STRUCTURE AS ACTIVE INGREDIENT | 고려대학교 산학협력단 | 2023-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240408072-A1 | COMPOSITION FOR PREVENTING OR TREATING GRAVES' DISEASE COMPRISING COMPOUND CONTAINING AN IMIDAZOPYRIDINE STRUCTURE AS ACTIVE INGREDIENT | TPO, GIPR, TRHDE | MAPT 4662/4885GAA 467/4885ALDH1A1 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.