Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | RAPGEF3 | O95398 | 4/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbonyl Cyanide M-Chlorophenylhydrazone SCHEMBL28977410 | 0.89 | MAPT (0.76) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL379196 | 0.71 | MAPT (0.57) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| Carbonyl Cyanide M-Chlorophenylhydrazone SCHEMBL379195 | 0.71 | MAPT (1.00) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| Carbonyl Cyanide M-Chlorophenylhydrazone SCHEMBL29353613 | 0.71 | MAPT (1.00) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL3817543 | 0.70 | MAPT (0.48) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL3817544 | 0.70 | MAPT (0.48) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL2343565 | 0.69 | MAPT (0.71) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL15515688 | 0.69 | MAPT (0.53) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL28115196 | 0.69 | MAPT (0.53) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL28115197 | 0.69 | MAPT (0.53) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894317-A | Micromolecular compound with naphthylthiophenol ether structure and application thereof | 杭州天玑济世生物科技有限公司 | 2023-04-04 | — | — | CN | disclosed |