Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274638 | 1.00 | KDM4E (0.47) | KDM4ESLC6A3SLC6A2SLC6A4CYP1A2 | |
| SCHEMBL10170706 | 0.81 | KDM4E (0.53) | KDM4ESLC6A3SLC6A2SLC6A4CYP1A2 | |
| SCHEMBL1685422 | 0.81 | KDM4E (0.53) | KDM4ESLC6A3SLC6A2SLC6A4CYP1A2 | |
| SCHEMBL10170707 | 0.81 | KDM4E (0.53) | KDM4ESLC6A3SLC6A2SLC6A4CYP1A2 | |
| SCHEMBL8599699 | 0.81 | CYP1A2 (0.55) | KDM4ESLC6A3SLC6A2SLC6A4CYP1A2 | |
| SCHEMBL24586223 | 0.80 | CYP3A4 (0.41) | KDM4ESLC6A3SLC6A2SLC6A4CYP1A2 | |
| SCHEMBL14915338 | 0.80 | CYP3A4 (0.41) | KDM4ESLC6A3SLC6A2SLC6A4CYP1A2 | |
| SCHEMBL29925482 | 0.80 | CYP3A4 (0.41) | KDM4ESLC6A3SLC6A2SLC6A4CYP1A2 | |
| SCHEMBL15037013 | 0.77 | CASP1 (0.57) | KDM4ESLC6A3CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL10893337 | 0.76 | LMNA (0.55) | KDM4ESLC6A3SLC6A2SLC6A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894247-B | Preparation method and intermediate of 1, 3-disubstituted-2-propanone compound | 迈克斯(如东)化工有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-115894247-A | Preparation method of 1,3-disubstituted-2-acetone compound and intermediate thereof | 迈克斯(如东)化工有限公司 | 2023-04-04 | — | — | CN | disclosed |