Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | BLM | P54132 | 2/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | MPO | P05164 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27739690 | 1.00 | KMT2A (0.76) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL15542651 | 0.88 | KMT2A (0.97) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL15542649 | 0.88 | KMT2A (0.97) | KMT2AKDM4EMAPTLMNATSHR | |
| D-Tryptophan SCHEMBL29029183 | 0.88 | KMT2A (0.97) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL27705509 | 0.88 | KDM4E (0.80) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL23141133 | 0.87 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL4732052 | 0.87 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL19161120 | 0.87 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL7327 | 0.87 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL1120026 | 0.87 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048460-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY | 2010-02-25 | — | — | US | disclosed |
| US-20100009916-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | BOKVIST BENGT KRISTER | 2010-01-14 | — | — | US | disclosed |
| US-7582608-B2 | Selective VPAC2 receptor peptide agonists | ELI LILLY AND COMPANY (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090118167-A1 | Selective Vpac2 Receptor Peptide Agonists | ELI LILLY AND COMPANY PATENT DIVISION (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090082276-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY | 2009-03-26 | — | — | US | disclosed |
| US-20080318845-A1 | Selective Vpac2 Receptor Peptide Agonists | ELI LILLY AND COMPANY (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080234198-A1 | Selective Vpac2 Receptor Peptide Agonists | ELI LILLY AND COMPANY | 2008-09-25 | — | — | US | disclosed |
| US-20080194482-A1 | Selective Apac2 Receptor Peptide Agonists | ELI LILLY AND COMPANY | 2008-08-14 | — | — | US | disclosed |
| EP-1942941-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY (US) | 2008-07-16 | — | — | EP | disclosed |
| US-20080146500-A1 | Selective Vpac2 Receptor Peptide Agonists | ELI LILLY AND COMPANY | 2008-06-19 | — | — | US | disclosed |
| EP-1781692-A2 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2007050651-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY (US) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007021498-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY (US) | 2007-02-22 | — | — | WO | disclosed |
| EP-1753780-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | disclosed |
| WO-2006023356-A2 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY (US) | 2006-03-02 | — | — | WO | disclosed |
| WO-2006023358-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY (US) | 2006-03-02 | — | — | WO | disclosed |
| WO-2006023367-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY (US) | 2006-03-02 | — | — | WO | disclosed |
| WO-2005113593-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | ELI LILLY AND COMPANY (US) | 2005-12-01 | — | — | WO | disclosed |
| US-3993795-A | Process for fortifying foodstuffs with pro-lysines | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | KMT2A 1733/4885KDM4E 1868/4885MAPT 585/4885 |
| US-20080318845-A1 | Selective Vpac2 Receptor Peptide Agonists | VIPR2, VIPR1, GPR119 | KMT2A 2699/4885KDM4E 2729/4885MAPT 3963/4885 |
| US-20100048460-A1 | SELECTIVE VPAC2 RECEPTOR PEPTIDE AGONISTS | VIPR2, VIPR1, GPR119 | KMT2A 2682/4885KDM4E 2686/4885MAPT 4106/4885 |
| US-20080146500-A1 | Selective Vpac2 Receptor Peptide Agonists | VIPR2, VIPR1, GPR119 | KMT2A 2682/4885KDM4E 2686/4885MAPT 4106/4885 |
| US-20090118167-A1 | Selective Vpac2 Receptor Peptide Agonists | VIPR1, VIPR2, AVPR1A | KMT2A 1761/4885KDM4E 2298/4885MAPT 2941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.