Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042064 | 0.86 | ALDH1A1 (0.40) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL6614428 | 0.84 | KMT2A (0.37) | ALDH1A1GAAHPGDHTTMAPT | |
| SCHEMBL3027577 | 0.78 | ALDH1A1 (0.45) | ALDH1A1GAAGFER | |
| SCHEMBL5734446 | 0.77 | HDAC6 (0.37) | ALDH1A1GAAHPGDALOX15FFAR2 | |
| SCHEMBL3038281 | 0.73 | ITGB1 (0.42) | MAPT | |
| SCHEMBL5736347 | 0.69 | MAPT (0.44) | ALDH1A1GAAPKMHTTFFAR2 | |
| SCHEMBL5734992 | 0.68 | GAA (0.34) | ALDH1A1GAAHPGDHTTMAPT | |
| Water SCHEMBL7984015 | 0.67 | KMT2A (0.39) | ALDH1A1GAAHTTMAPT | |
| Bromide SCHEMBL8001925 | 0.67 | MAPT (0.42) | ALDH1A1GAAPKMHTTFFAR2 | |
| SCHEMBL8001928 | 0.65 | MAPT (0.41) | GAAHTTFFAR2MAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | LINDERMAN RUSSELL J (US) | 2004-02-19 | — | — | US | claimed |
| US-6660770-B2 | Inhibit digestion by terminating or blocking synthesis of digestive enzymes by activating trypsin modulating oostatic factor receptor | NORTH CAROLINA STATE UNIVERSITY | 2003-12-09 | — | — | US | claimed |
| EP-1241941-B1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | UNIV NORTH CAROLINA STATE (US) | 2003-06-18 | — | — | EP | claimed |
| US-6521664-B1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2003-02-18 | — | — | US | claimed |
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2002-12-19 | — | — | US | claimed |
| WO-2002098220-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-12-12 | — | — | WO | claimed |
| EP-1241941-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-09-25 | — | — | EP | claimed |
| WO-2001041543-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-06-14 | — | — | WO | claimed |
| US-20100217007-A1 | CHEMICAL PROCESS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| EP-1928869-B1 | CHEMICAL PROCESS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-03-17 | — | — | EP | disclosed |
| EP-1928869-A1 | CHEMICAL PROCESS | Syngeta Participations AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007020460-A1 | CHEMICAL PROCESS | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
| US-20040209776-A1 | Azole derivatives useful as insecticide | FAROOQ SALEEM | 2004-10-21 | — | — | US | disclosed |
| CN-1533389-A | Azole derivatives useful as insecticide | — | 2004-09-29 | — | — | CN | disclosed |
| EP-1241941-B1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | UNIV NORTH CAROLINA STATE (US) | 2003-06-18 | — | — | EP | disclosed |
| US-6521664-B1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2003-02-18 | — | — | US | disclosed |
| WO-2003011861-A1 | AZOLE DERIVATIVES USEFUL AS INSECTICIDE | SYNGENTA LIMITED (GB) | 2003-02-13 | — | — | WO | disclosed |
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2002-12-19 | — | — | US | disclosed |
| EP-1241941-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001041543-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | VIP, ANPEP, APEH | ALDH1A1 1396/4885GAA 391/4885USP2 2238/4885 |
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | VIP, ANPEP, APEH | ALDH1A1 1396/4885GAA 391/4885USP2 2238/4885 |
| US-20040209776-A1 | Azole derivatives useful as insecticide | CYP8B1, HRH2, API5 | ALDH1A1 1410/4885GAA 3356/4885USP2 2445/4885 |
| US-20100217007-A1 | CHEMICAL PROCESS | CBR3, RCC2, CBR1 | ALDH1A1 520/4885GAA 3690/4885USP2 3262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.