SCHEMBL30360754

SCHEMBL30360754

Cc1cccc(Oc2cccc(C#N)c2C#N)c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AR P10275 7/20 0.58
ALDH1A1 P00352 4/20 0.51
GAA P10253 2/20 0.51
SMN1; SMN2 Q16637 3/20 0.45
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ACHE P22303 1/20 0.42
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CRHR1 P34998 1/20 0.41
EPAS1 Q99814 1/20 0.41
TBXA2R P21731 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20510888 1.00 AR (0.58) ARALDH1A1GAASMN1; SMN2KDM4E
SCHEMBL12406455 0.90 ALDH1A1 (0.62) ARALDH1A1GAASMN1; SMN2L3MBTL1
SCHEMBL3571772 0.89 SMN1; SMN2 (0.46) ARALDH1A1GAASMN1; SMN2KDM4E
SCHEMBL21352429 0.89 SMN1; SMN2 (0.50) ARALDH1A1GAASMN1; SMN2KDM4E
SCHEMBL30426714 0.87 AR (0.66) ARALDH1A1GAASMN1; SMN2POLB
SCHEMBL6177523 0.83 AR (0.52) ARALDH1A1GAASMN1; SMN2KDM4E
SCHEMBL22904530 0.83 AR (0.52) ARALDH1A1GAASMN1; SMN2L3MBTL1
SCHEMBL9746110 0.83 SMN1; SMN2 (0.52) ARALDH1A1GAASMN1; SMN2KDM4E
SCHEMBL669346 0.82 SMN1; SMN2 (0.57) ARALDH1A1GAASMN1; SMN2KDM4E
SCHEMBL31183019 0.81 MAOB (0.47) ARALDH1A1GAASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110461814-B Resin blends, prepregs and articles containing a phthalonitrile reactive diluent and a bisphthalonitrile resin 3M创新有限公司 2023-04-14 CN disclosed