SCHEMBL669346

SCHEMBL669346

N#Cc1cccc(Oc2ccccc2)c1C#N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.57
KDM4E B2RXH2 2/20 0.57
POLB P06746 2/20 0.54
GAA P10253 1/20 0.54
MAPT P10636 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPK14 Q16539 1/20 0.43
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2C9 P11712 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PIN1 Q13526 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD11B1 P28845 1/20 0.40
LPAR1 Q92633 1/20 0.40
LPAR5 Q9H1C0 1/20 0.40
HPGD P15428 1/20 0.40
AR P10275 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28193306 0.98 SMN1; SMN2 (0.56) SMN1; SMN2KDM4EPOLBGAAMAPT
SCHEMBL9746326 0.96 SMN1; SMN2 (0.54) SMN1; SMN2KDM4EPOLBGAAMAPT
SCHEMBL9745662 0.96 SMN1; SMN2 (0.58) SMN1; SMN2KDM4EPOLBGAAMAPT
SCHEMBL9745478 0.96 SMN1; SMN2 (0.58) SMN1; SMN2KDM4EPOLBGAAMAPT
SCHEMBL9746110 0.93 SMN1; SMN2 (0.52) SMN1; SMN2KDM4EPOLBGAAMAPT
Dimethylamine SCHEMBL1361903 0.93 POLB (0.53) SMN1; SMN2KDM4EPOLBGAAMAPT
SCHEMBL9746273 0.92 SMN1; SMN2 (0.54) SMN1; SMN2KDM4EPOLBGAAMAPT
SCHEMBL21352429 0.89 SMN1; SMN2 (0.50) SMN1; SMN2KDM4EPOLBGAAMAPT
SCHEMBL17090701 0.86 MAPT (0.47) SMN1; SMN2KDM4EPOLBGAAMAPT
SCHEMBL8626899 0.86 SMN1; SMN2 (0.50) SMN1; SMN2KDM4EPOLBGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109608489-A The phthalonitrile-terminated siliceous poly (arylene ether nitrile) oligomer of one kind, its solidfied material and the preparation method and application thereof 中国科学院化学研究所 2019-04-12 CN claimed
CN-107903189-A It is a kind of phthalonitrile-terminated containing fluorene structured poly (arylene ether nitrile) oligomer, solidfied material and preparation method thereof 中国科学院化学研究所 2018-04-13 CN claimed
US-8039576-B2 Aromatic ether and alkynyl containing phthalonitriles THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2011-10-18 US claimed
US-20090069484-A1 AROMATIC ETHER AND ALKYNYL CONTAINING PHTHALONITRILES THE GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2009-03-12 US claimed
EP-3965738-B1 METHOD FOR PRODUCTION OF LIPOSOMES UNIV DO MINHO (PT) 2025-08-06 EP disclosed
CN-118490844-A Water-soluble phthalocyanine/polydopamine nanosphere and preparation method and application thereof 中科检测技术服务(重庆)有限公司 2024-08-16 CN disclosed
CN-117736232-A Green synthesis method of high-yield alpha (beta) -tetra-substituent-dihydroxyl silicon phthalocyanine derivative 浙江工业大学 2024-03-22 CN disclosed
CN-110461814-B Resin blends, prepregs and articles containing a phthalonitrile reactive diluent and a bisphthalonitrile resin 3M创新有限公司 2023-04-14 CN disclosed
US-20220241203-A1 METHOD FOR PRODUCTION OF LIPOSOMES UNIVERSIDADE DO MINHO (PT) 2022-08-04 US disclosed
US-11292891-B2 Resin blends containing a phthalonitrile reactive diluent and a diphthalonitrile resin, prepregs, and articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US disclosed
US-20200131336-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2020-04-30 US disclosed
EP-3601215-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES 3M Innovative Properties Company (US) 2020-02-05 EP disclosed
US-5149800-A For natural or synthetic resins, especially polyolefins and polyurethane foams MILLIKEN RESEARCH CORPORATION (US) 1992-09-22 US disclosed
US-5135717-A Imaging therapy BRITISH TECHNOLOGY GROUP USA INC. (US) 1992-08-04 US disclosed
US-5135972-A For polymeric substrates MILLIKEN RESEARCH CORPORATION (US) 1992-08-04 US disclosed
EP-0484027-A1 Polysubstituted phthalocyanines ZENECA LIMITED (GB) 1992-05-06 EP disclosed
EP-0434727-A1 RED-SHIFTED PHTHALOCYANINE AND TETRABENZTRIAZAPORPHYRIN REAGENTS BRITISH TECHNOLOGY GROUP (USA) INCORPORATED (US) 1991-07-03 EP disclosed
EP-0398620-A2 Poly(oxyalkylene) modified phthalocyanine colorants MILLIKEN RESEARCH CORPORATION (US) 1990-11-22 EP disclosed
WO-1990002747-A1 RED-SHIFTED PHTHALOCYANINE AND TETRABENZTRIAZAPORPHYRIN REAGENTS ULTRA DIAGNOSTICS CORPORATION (US) 1990-03-22 WO disclosed
US-4152171-A CRYSTAL GROWTH INHIBITORS CIBA-GEIGY CORPORATION (US) 1979-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131336-A1 RESIN BLENDS CONTAINING A PHTHALONITRILE REACTIVE DILUENT AND A DIPHTHALONITRILE RESIN, PREPREGS, AND ARTICLES PNN, RPN1, DCXR SMN1; SMN2 2650/4885KDM4E 2848/4885POLB 1900/4885
US-11292891-B2 Resin blends containing a phthalonitrile reactive diluent and a diphthalonitrile resin, prepregs, and articles PNN, RPN1, DCXR SMN1; SMN2 2650/4885KDM4E 2848/4885POLB 1900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.