SCHEMBL30360776

SCHEMBL30360776

Brc1coc2cc3ccccc3cc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.37
MAOB P27338 3/20 0.35
MAOA P21397 2/20 0.35
TTR P02766 1/20 0.35
PIN1 Q13526 1/20 0.34
ALDH1A1 P00352 3/20 0.33
NQO1 P15559 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
PRKDC P78527 4/20 0.31
KDM4E B2RXH2 2/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28592231 1.00 CYP2A6 (0.37) CYP2A6MAOBMAOATTRPIN1
SCHEMBL23919117 0.75 KCNA3 (0.46) CYP2A6MAOAPIN1ALDH1A1NQO1
SCHEMBL6008 0.73 MAOB (0.44) MAOBMAOAALDH1A1KDM4EMAPT
SCHEMBL29874833 0.73 MAOB (0.44) MAOBMAOAALDH1A1KDM4EMAPT
SCHEMBL27290456 0.72 AHR (0.49) MAOAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL24489802 0.71 PTPN1 (0.54) ALDH1A1MEN1KMT2APRKDCKDM4E
SCHEMBL1995246 0.71 CA1 (0.42) CYP2A6PIN1ALDH1A1KMT2AKDM4E
SCHEMBL30695267 0.70 PTPN1 (0.53) MAOBMAOAALDH1A1MEN1KMT2A
SCHEMBL28006934 0.70 PTPN1 (0.53) MAOBMAOAALDH1A1MEN1KMT2A
SCHEMBL17228470 0.69 LOXL2 (0.40) MAOBMAOAALDH1A1HIF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112876498-B Polycyclic aromatic compound and organic electroluminescent element containing same 北京八亿时空液晶科技股份有限公司 2023-04-18 CN disclosed