Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | IGLV6-57 | P01721 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839406 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HPGDARALDH2KDM4E | |
| SCHEMBL20839115 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HPGDARALDH2KDM4E | |
| SCHEMBL31622307 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HPGDARALDH2KDM4E | |
| SCHEMBL30055780 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HPGDARALDH2KDM4E | |
| SCHEMBL20839429 | 0.88 | ALDH1A1 (0.58) | ALDH1A1HPGDARALDH2KDM4E | |
| SCHEMBL20839101 | 0.88 | ALDH1A1 (0.58) | ALDH1A1HPGDARALDH2KDM4E | |
| SCHEMBL30360940 | 0.88 | ALDH1A1 (0.58) | ALDH1A1HPGDARALDH2KDM4E | |
| SCHEMBL20839103 | 0.88 | ALDH1A1 (0.58) | ALDH1A1HPGDARALDH2KDM4E | |
| SCHEMBL30360898 | 0.88 | ALDH1A1 (0.58) | ALDH1A1HPGDARALDH2KDM4E | |
| SCHEMBL20839059 | 0.88 | ALDH1A1 (0.77) | ALDH1A1HPGDARALDH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | claimed |
| EP-3684762-B1 | COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER | LEAD DISCOVERY CENTER GMBH (DE) | 2023-05-03 | — | — | EP | claimed |
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-3684762-B1 | COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER | LEAD DISCOVERY CENTER GMBH (DE) | 2023-05-03 | — | — | EP | disclosed |