Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839103 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HPGDCA12CA9KDM4E | |
| SCHEMBL20839101 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HPGDCA12CA9KDM4E | |
| SCHEMBL20839115 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL30055780 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL30360855 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL20839406 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL31622307 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4ERECQLAR | |
| SCHEMBL20839468 | 0.88 | ALDH1A1 (0.75) | ALDH1A1HPGDCA12CA9KDM4E | |
| SCHEMBL20839066 | 0.88 | ALDH1A1 (0.75) | ALDH1A1HPGDCA12CA9KDM4E | |
| SCHEMBL30763026 | 0.88 | ALDH1A1 (0.75) | ALDH1A1HPGDCA12CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | claimed |
| EP-3684762-B1 | COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER | LEAD DISCOVERY CENTER GMBH (DE) | 2023-05-03 | — | — | EP | claimed |
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-3684762-B1 | COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER | LEAD DISCOVERY CENTER GMBH (DE) | 2023-05-03 | — | — | EP | disclosed |